-

Digestive Enzymes

                      Enzymes are biological catalyst which is responsible for degradation of complex
                      molecule(food) into simple(food) & absorbable form.

                       Enzyme enhance the rate of reaction by decreasing the activation energy of substrate.

                        Few important digestive enzyme are-

Trypsin - trypsin is secreted from pancreas (mix gland) as a trypsinogen.
               
  • It cleaves the peptides at carboxyl side (c-side) of lysine (k) & arginine(R),which is basic amino acids
  • .Exception,if lysine or arginine is followed by proline trypsin does not act on that peptide because 3D cleft or active site of trypsin does not fit on that situation.
  • Pancreas secrets three isoform of Trypsinogen i.e.trypsiogen-1(cationic),trypsinogen-2(anionic) & mesotrpsinogen (trypsinogen-3){that provide the resistance to trypsin inhibitor}.
Chymotrypsin--cleaves the peptide at c-side of aromatic amino                               acid(tryptophan,tyrosin&phenylalanine).

Carboxypeptidase- are of two types-1.Carboxypeptidase-A(A for aliphatic or aromatic both) remove the C-terminal of aliphatic or aromatic amino acid.2. Carboxypeptidase-B(B for basic) remove the C-terminal of basic amino acid.
Elastase-hydrolysed the c-side of small amino acid(gly & ala).

Comments

Post a Comment

Popular posts from this blog

-
Image
Dreams don't work unless you do  The scientific study of dreams is known as   oneirology . People are more likely to remember their dreams if they wake up during the REM phase( Rapid Eye Movement ). About 80% of neonatal and newborn  sleep  time is REM sleep, suggesting a tremendous amount of time dreaming. According to Plato, dreams originate in the organs of the belly. Plato describes the liver in particular as the biological seat of dreams. The average person has about 1,460 dreams a year. That’s about four per night.   Modern research has shown that a sharp decrease in daily calories results in fewer nocturnal ejaculations in  men  and an overall decrease in the sexual themes of dreams. During REM  sleep , the flow of blood to the brain increases, as does the brain’s temperature. Additionally, both the penis and the clitoris become erect .   Most of us dream every 90 minutes, and the longest dreams (30-45 minutes) occur in the morning. V...
Read more
-
How corn silk inhibit the melanin(pigment) production  In maize  ,the female flower produce Corn silk,which is generally regarded as waste a discarded. Corn silk contain protein ,phenolic compound particularly flavonoids,vitamins,carbohydrates calcium,potassium,sodium salt ,volatile oils &,steroids such as sitosterol and stigmasterol. Researcher in Korea have reported that silk decreased melanin production by about 37%. Melanin is an natural pigment that responsable for skin color. It is produced by a cell called  melanocyte. Melanin production is inhibited by corn silk how?               Biosynthesis of melanin starts with oxidation of tyrosine by tyrosinase . T he corn silk extract did not suppress tyrosinase activity but greatly reduced the expression of tyrosinase in Melan-A cells. In addition, corn silk extract was applied to the human face with hyperpigmentation, and skin color was measured to examine the de...
Read more